Búsqueda | Biblioteca Virtual en Salud

1.

The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.

Issa, Ghayas C; Aldoss, Ibrahim; DiPersio, John; Cuglievan, Branko; Stone, Richard; Arellano, Martha; Thirman, Michael J; Patel, Manish R; Dickens, David S; Shenoy, Shalini; Shukla, Neerav; Kantarjian, Hagop; Armstrong, Scott A; Perner, Florian; Perry, Jennifer A; Rosen, Galit; Bagley, Rebecca G; Meyers, Michael L; Ordentlich, Peter; Gu, Yu; Kumar, Vinit; Smith, Steven; McGeehan, Gerard M; Stein, Eytan M.

Nature ; 615(7954): 920-924, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36922593

2.

MEN1 mutations mediate clinical resistance to menin inhibition.

Perner, Florian; Stein, Eytan M; Wenge, Daniela V; Singh, Sukrit; Kim, Jeonghyeon; Apazidis, Athina; Rahnamoun, Homa; Anand, Disha; Marinaccio, Christian; Hatton, Charlie; Wen, Yanhe; Stone, Richard M; Schaller, David; Mowla, Shoron; Xiao, Wenbin; Gamlen, Holly A; Stonestrom, Aaron J; Persaud, Sonali; Ener, Elizabeth; Cutler, Jevon A; Doench, John G; McGeehan, Gerard M; Volkamer, Andrea; Chodera, John D; Nowak, Radoslaw P; Fischer, Eric S; Levine, Ross L; Armstrong, Scott A; Cai, Sheng F.

Nature ; 615(7954): 913-919, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36922589

3.

Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.

Yoshimi, Akihide; Lin, Kuan-Ting; Wiseman, Daniel H; Rahman, Mohammad Alinoor; Pastore, Alessandro; Wang, Bo; Lee, Stanley Chun-Wei; Micol, Jean-Baptiste; Zhang, Xiao Jing; de Botton, Stephane; Penard-Lacronique, Virginie; Stein, Eytan M; Cho, Hana; Miles, Rachel E; Inoue, Daichi; Albrecht, Todd R; Somervaille, Tim C P; Batta, Kiran; Amaral, Fabio; Simeoni, Fabrizio; Wilks, Deepti P; Cargo, Catherine; Intlekofer, Andrew M; Levine, Ross L; Dvinge, Heidi; Bradley, Robert K; Wagner, Eric J; Krainer, Adrian R; Abdel-Wahab, Omar.

Nature ; 574(7777): 273-277, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31578525

4.

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.

Döhner, Hartmut; Wei, Andrew H; Appelbaum, Frederick R; Craddock, Charles; DiNardo, Courtney D; Dombret, Hervé; Ebert, Benjamin L; Fenaux, Pierre; Godley, Lucy A; Hasserjian, Robert P; Larson, Richard A; Levine, Ross L; Miyazaki, Yasushi; Niederwieser, Dietger; Ossenkoppele, Gert; Röllig, Christoph; Sierra, Jorge; Stein, Eytan M; Tallman, Martin S; Tien, Hwei-Fang; Wang, Jianxiang; Wierzbowska, Agnieszka; Löwenberg, Bob.

Blood ; 140(12): 1345-1377, 2022 09 22.

Artículo en Inglés | MEDLINE | ID: mdl-35797463

5.

Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies.

Krystel-Whittemore, Melissa; Petrova-Drus, Kseniya; Ptashkin, Ryan N; Ewalt, Mark D; Yao, JinJuan; Liu, Ying; Zhu, Menglei; Benhamida, Jamal; Durham, Benjamin; Kumar, Jyoti; Nafa, Khedoudja; Kiecka, Iwona; Bowman, Anita S; Gedvilaite, Erika; Casanova, Jacklyn; Lin, Yun-Te; Mohanty, Abhinita S; Rana, Satshil; Rema, Anoop Balakrishnan; Rijo, Ivelise; Chaves, Nelio; Salazar, Paulo; Yun, Anita; Lachhander, Sean; Wang, Wei; Haque, Mohammad S; Xiao, Wenbin; Roshal, Mikhail; Giralt, Sergio; Salles, Gilles; Rampal, Raajit; Stein, Eytan M; Perales, Miguel-Angel; Horwitz, Steven; Jakubowski, Ann; Ponce, Doris; Markova, Alina; Birsoy, Ozge; Mandelker, Diana; Mantha, Simon; Dogan, Ahmet; Benayed, Ryma; Ladanyi, Marc; Berger, Michael F; Brannon, A Rose; Zehir, Ahmet; Vanderbilt, Chad; Arcila, Maria E.

Haematologica ; 2024 Mar 07.

Artículo en Inglés | MEDLINE | ID: mdl-38450530

6.

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations.

Intlekofer, Andrew M; Shih, Alan H; Wang, Bo; Nazir, Abbas; Rustenburg, Ariën S; Albanese, Steven K; Patel, Minal; Famulare, Christopher; Correa, Fabian M; Takemoto, Naofumi; Durani, Vidushi; Liu, Hui; Taylor, Justin; Farnoud, Noushin; Papaemmanuil, Elli; Cross, Justin R; Tallman, Martin S; Arcila, Maria E; Roshal, Mikhail; Petsko, Gregory A; Wu, Bin; Choe, Sung; Konteatis, Zenon D; Biller, Scott A; Chodera, John D; Thompson, Craig B; Levine, Ross L; Stein, Eytan M.

Nature ; 559(7712): 125-129, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-29950729

7.

Entospletinib with decitabine in acute myeloid leukemia with mutant TP53 or complex karyotype: A phase 2 substudy of the Beat AML Master Trial.

Duong, Vu H; Ruppert, Amy S; Mims, Alice S; Borate, Uma; Stein, Eytan M; Baer, Maria R; Stock, Wendy; Kovacsovics, Tibor; Blum, William; Arellano, Martha L; Schiller, Gary J; Olin, Rebecca L; Foran, James M; Litzow, Mark R; Lin, Tara L; Patel, Prapti A; Foster, Matthew C; Redner, Robert L; Al-Mansour, Zeina; Cogle, Christopher R; Swords, Ronan T; Collins, Robert H; Vergilio, Jo-Anne; Heerema, Nyla A; Rosenberg, Leonard; Yocum, Ashley O; Marcus, Sonja; Chen, Timothy; Druggan, Franchesca; Stefanos, Mona; Gana, Theophilus J; Shoben, Abigail B; Druker, Brian J; Burd, Amy; Byrd, John C; Levine, Ross L; Boyiadzis, Michael M.

Cancer ; 129(15): 2308-2320, 2023 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-37078412

8.

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.

Stein, Eytan M; DiNardo, Courtney D; Fathi, Amir T; Mims, Alice S; Pratz, Keith W; Savona, Michael R; Stein, Anthony S; Stone, Richard M; Winer, Eric S; Seet, Christopher S; Döhner, Hartmut; Pollyea, Daniel A; McCloskey, James K; Odenike, Olatoyosi; Löwenberg, Bob; Ossenkoppele, Gert J; Patel, Prapti A; Roshal, Mikhail; Frattini, Mark G; Lersch, Frederik; Franovic, Aleksandra; Nabhan, Salah; Fan, Bin; Choe, Sung; Wang, Hongfang; Wu, Bin; Hua, Lei; Almon, Caroline; Cooper, Michael; Kantarjian, Hagop M; Tallman, Martin S.

Blood ; 137(13): 1792-1803, 2021 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-33024987

9.

Routine clinical parameters and laboratory testing predict therapy-related myeloid neoplasms after treatment for breast cancer.

Petrone, Giulia; Gaulin, Charles; Derkach, Andriy; Kishtagari, Ashwin; Robson, Mark E; Parameswaran, Rekha; Stein, Eytan M.

Haematologica ; 108(1): 161-170, 2023 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-35770528

10.

Molecular predictors of immunophenotypic measurable residual disease clearance in acute myeloid leukemia.

Stahl, Maximilian; Derkach, Andriy; Farnoud, Noushin; Bewersdorf, Jan Philipp; Robinson, Troy; Famulare, Christopher; Cho, Christina; Devlin, Sean; Menghrajani, Kamal; Patel, Minal A; Cai, Sheng F; Miles, Linde A; Bowman, Robert L; Geyer, Mark B; Dunbar, Andrew; Epstein-Peterson, Zachary D; McGovern, Erin; Schulman, Jessica; Glass, Jacob L; Taylor, Justin; Viny, Aaron D; Stein, Eytan M; Getta, Bartlomiej; Arcila, Maria E; Gao, Qi; Barker, Juliet; Shaffer, Brian C; Papadopoulos, Esperanza B; Gyurkocza, Boglarka; Perales, Miguel-Angel; Abdel-Wahab, Omar; Levine, Ross L; Giralt, Sergio A; Zhang, Yanming; Xiao, Wenbin; Pai, Nidhi; Papaemmanuil, Elli; Tallman, Martin S; Roshal, Mikhail; Goldberg, Aaron D.

Am J Hematol ; 98(1): 79-89, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36251406

11.

Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.

Roboz, Gail J; DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Mims, Alice S; Prince, Gabrielle T; Altman, Jessica K; Arellano, Martha L; Donnellan, Will; Erba, Harry P; Mannis, Gabriel N; Pollyea, Daniel A; Stein, Anthony S; Uy, Geoffrey L; Watts, Justin M; Fathi, Amir T; Kantarjian, Hagop M; Tallman, Martin S; Choe, Sung; Dai, David; Fan, Bin; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Hickman, Denice; Liu, Hua; Agresta, Samuel V; Wu, Bin; Attar, Eyal C; Stone, Richard M.

Blood ; 135(7): 463-471, 2020 02 13.

Artículo en Inglés | MEDLINE | ID: mdl-31841594

12.

Atypical pathogens presenting with pulmonary consolidations detected by cell-free DNA next-generation sequencing in patients with hematologic malignancies.

Caldararo, Mario; Algazaq, Jumanah; Schmidt, Elizabeth; Joanow, Alexa; Mariano, Amanda; Predmore, Jacqueline; Politikos, Ioannis; Cho, Christina; Stein, Eytan M; Wen, Xiaoyoun; Travis, William D; Raible, Kevin; Cintron, Melvili; Babady, N Esther; Papanicolaou, Genovefa; Lee, Yeon Joo.

Infect Dis Clin Pract (Baltim Md) ; 30(2)2022 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-35586753

13.

Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial.

DiNardo, Courtney D; Schuh, Andre C; Stein, Eytan M; Montesinos, Pau; Wei, Andrew H; de Botton, Stéphane; Zeidan, Amer M; Fathi, Amir T; Kantarjian, Hagop M; Bennett, John M; Frattini, Mark G; Martin-Regueira, Patricia; Lersch, Frederik; Gong, Jing; Hasan, Maroof; Vyas, Paresh; Döhner, Hartmut.

Lancet Oncol ; 22(11): 1597-1608, 2021 11.

Artículo en Inglés | MEDLINE | ID: mdl-34672961

14.

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.

DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Roboz, Gail J; Altman, Jessica K; Mims, Alice S; Swords, Ronan; Collins, Robert H; Mannis, Gabriel N; Pollyea, Daniel A; Donnellan, Will; Fathi, Amir T; Pigneux, Arnaud; Erba, Harry P; Prince, Gabrielle T; Stein, Anthony S; Uy, Geoffrey L; Foran, James M; Traer, Elie; Stuart, Robert K; Arellano, Martha L; Slack, James L; Sekeres, Mikkael A; Willekens, Christophe; Choe, Sung; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Yang, Hua; Dai, David; Fan, Bin; Goldwasser, Meredith; Liu, Hua; Agresta, Sam; Wu, Bin; Attar, Eyal C; Tallman, Martin S; Stone, Richard M; Kantarjian, Hagop M.

N Engl J Med ; 378(25): 2386-2398, 2018 Jun 21.

Artículo en Inglés | MEDLINE | ID: mdl-29860938

15.

Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.

Stein, Eytan M; DiNardo, Courtney D; Fathi, Amir T; Pollyea, Daniel A; Stone, Richard M; Altman, Jessica K; Roboz, Gail J; Patel, Manish R; Collins, Robert; Flinn, Ian W; Sekeres, Mikkael A; Stein, Anthony S; Kantarjian, Hagop M; Levine, Ross L; Vyas, Paresh; MacBeth, Kyle J; Tosolini, Alessandra; VanOostendorp, Jason; Xu, Qiang; Gupta, Ira; Lila, Thomas; Risueno, Alberto; Yen, Katharine E; Wu, Bin; Attar, Eyal C; Tallman, Martin S; de Botton, Stéphane.

Blood ; 133(7): 676-687, 2019 02 14.

Artículo en Inglés | MEDLINE | ID: mdl-30510081

16.

Differentiation syndrome with lower-intensity treatments for acute myeloid leukemia.

Fathi, Amir T; Stein, Eytan M; DiNardo, Courtney D; Levis, Mark J; Montesinos, Pau; de Botton, Stéphane.

Am J Hematol ; 96(6): 735-746, 2021 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-33625753

17.

IDH2 inhibition in AML.

Stein, Eytan M.

Blood ; 141(2): 124-125, 2023 01 12.

Artículo en Inglés | MEDLINE | ID: mdl-36633887

18.

A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML.

Fathi, Amir T; Erba, Harry P; Lancet, Jeffrey E; Stein, Eytan M; Ravandi, Farhad; Faderl, Stefan; Walter, Roland B; Advani, Anjali S; DeAngelo, Daniel J; Kovacsovics, Tibor J; Jillella, Anand; Bixby, Dale; Levy, Moshe Y; O'Meara, Megan M; Ho, Phoenix A; Voellinger, Jenna; Stein, Anthony S.

Blood ; 132(11): 1125-1133, 2018 09 13.

Artículo en Inglés | MEDLINE | ID: mdl-30045838

19.

A phase 1 trial of vadastuximab talirine as monotherapy in patients with CD33-positive acute myeloid leukemia.

Stein, Eytan M; Walter, Roland B; Erba, Harry P; Fathi, Amir T; Advani, Anjali S; Lancet, Jeffrey E; Ravandi, Farhad; Kovacsovics, Tibor; DeAngelo, Daniel J; Bixby, Dale; Faderl, Stefan; Jillella, Anand P; Ho, Phoenix A; O'Meara, Megan M; Zhao, Baiteng; Biddle-Snead, Charles; Stein, Anthony S.

Blood ; 131(4): 387-396, 2018 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-29196412

20.

The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.

Stein, Eytan M; Garcia-Manero, Guillermo; Rizzieri, David A; Tibes, Raoul; Berdeja, Jesus G; Savona, Michael R; Jongen-Lavrenic, Mojca; Altman, Jessica K; Thomson, Blythe; Blakemore, Stephen J; Daigle, Scott R; Waters, Nigel J; Suttle, A Benjamin; Clawson, Alicia; Pollock, Roy; Krivtsov, Andrei; Armstrong, Scott A; DiMartino, Jorge; Hedrick, Eric; Löwenberg, Bob; Tallman, Martin S.

Blood ; 131(24): 2661-2669, 2018 06 14.

Artículo en Inglés | MEDLINE | ID: mdl-29724899

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